Twist Bioscience develops various target enrichment panels to optimize next-generation sequencing workflows. In order to ensure the reliability of sequencing results when using target enrichment panels, quantifying the concentration can be performed at intake of the panel. This guideline outlines the materials required and the steps involved in quantifying target enrichment panels.

​​​​​​In the era of precision medicine, how can the power of AI be utilised to turn biological studies into the best possible targets? How can AI be applied to systems biology to bring the most effective targets to light? And how can we use these insights in the drug discovery process? In the webinar, 4 different experts will discuss the areas in which AI is bringing biological insights to the forefront, and Aaron Sato, Twist's CSO, will explain how Twist is enabling  the key players to write the Future of Biologics with Synthetic DNA and Machine Learning. Presented by: Gary An, Prof. & Vice Chair of Surgical Research, University of Vermont Aaron K. Sato, CSO, Twist Bioscience Enkelejda Miho, Prof. of Digital Life Sciences, The FHNW University of Applied Sciences and Arts Northwestern Switzerland Philip Kim, Prof., The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto

In the future, it is expected that the DNA methylation information of each individual will be used for early prevention of diseases and as a surrogate marker to improve lifestyle. However, the capture sequencing method is expensive and requires a large amount of DNA, which has been a challenge. At this time, with the cooperation of Twist Bioscience, they created a capture probe set to measure CpG at approximately 1,000 locations and evaluated it, especially for the amount of DNA required. As a result, it was confirmed that capture sequencing was possible with less than 200 ng of DNA compared to other reagents. In this talk, Dr. Shimizu presents their epigenome research at IMM, their recently published work on epigenetic age, and the results of the use of the Twist Bioscience Methylation detection system.