The SOLD library is a powerful tool that enables the exploration of the sequence space encoded by mutating multiple positions simultaneously scattered across the parental sequence to generate a diverse library of proteins.

New from Twist Bioscience, our Spread-Out Low Diversity (SOLD) libraries provide a quick and precise tool for mapping protein sequences to explore the complex relationship between the protein and its environment. Join us and hear from Twist Bioscience Product Manager Lucy Xu, to learn how a SOLD library could accelerate enzyme and protein engineering in your lab. In this webinar you will… Hear why Twist’s SOLD Libraries are ideal for scientists working on enzyme evolution and protein stability, who are looking to improve specificity, thermostability, processivity and/or performance. See how scattering diversity across the parental sequence enables mutations in multiple domains to be explored simultaneously. Understand how Twist’s silicon based DNA synthesis enables the best possible library versus NNK and trinucleotide mutagenesis (TRIM) technology, with balanced codon usage, avoidance of restriction sites and unnecessary mutations and a low error rate. Review what you can expect if you order a SOLD library – including NGS verification, and a library that is cloning-ready. View the Product Sheet

COMBINATORIAL | SOLD | SITE SATURATION